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Yankees vs Red Sox Opening Day Prediction and Betting Odds April 8

Yankee Stadium in the Bronx for a YRFI

Yankees vs Red Sox Betting Preview

Play Ball! WagerTalk MLB handicapper Andy Lang offers his Yankees vs Red Sox Opening Day betting preview for Friday, April 8. The Yankees and Red Sox both ended the 2021 regular season with identical 92-70 records, with Boston knocking New York out of last year’s playoffs in the Wild Card round.

Stay on top of the latest MLB updates direct from Las Vegas!

Friday, April 8 MLB Betting Notes, Courtesy of Caesars
Moneyline: New York Yankees -160 vs Boston Red Sox +150
Runline: Yankees -1.5 (+125) / Red Sox +1.5 (-145)
Total: 8 Runs (Over -120 / Under EV)
Game Time: 1:05pm ET / 10:05am PT
Where: Yankee Stadium in the Bronx
Weather: 59* with 10mph Winds Blowing Out to Center

Yankees vs Red Sox Analysis

Better late than never! The Yankees and Red Sox were supposed to kick things off on Thursday, but rain pushed Opening Day back to Friday. Boston edged out New York 10-8 in their regular season meetings last year, but the Yankees won six out of their ten games in the Bronx in 2021.

New Story For Red Sox

The Boston Red Sox will begin another season with high expectations. They challenged the Houston Astros for the American League Championship last season and hope to build on that success.

During the offseason the Sox lost Kyle Schwarber, Hunter Renfroe and Eduardo Rodriguez to free agency. However, the addition of Trevor Story will help fill the gap left by the two hitters mentioned.

Story put up 30 home run 30 double seasons in 2018 and 2019, and there is no reason to think he can’t do it again with a swing built for Fenway Park.

The Red Sox announced that their best starting pitcher, Chris Sale, will be placed on the 60-day injured list with a rib stress fracture.

Nathan Eovaldi will start for Boston, last season he went 11-9 with a 3.75 ERA and 195 strikeouts across 182 innings pitched. He’s posted similar numbers in the spring training with a 3.55 ERA and 16 strikeouts on 12.2 innings pitched.

Yankees Lineup Loaded With Power

The New York Yankees enter this season with hopes for their first World Series Championship since 2009. Getting knocked out last season in a one-game elimination against their rival was a hard loss for Yankees fans to take.

The Yankee lineup was already intimidating with sluggers like Aaron Judge, Giancarlo Stanton, Anthony Rizzo and Joey Gallo. The addition of a professional hitter like Josh Donaldson will only make for a stronger lineup. This offense will score plenty but they will also strikeout a ton.

Gerrit Cole will take the mound for New York on Thursday afternoon. Last season he went 16-8 with a 3.23 ERA and 243 strikeouts in 181.1 innings pitched. During the spring he has 6.75 ERA in only 5.1 innings pitched but he does have 10 strikeouts.

Yankees vs Red Sox Prediction

Both teams are pitching top line starters and both have a top ten rated bullpen coming into this season. They also both have stacked lineups, it feels like the over/under is an absolute coin flip.

To be honest, the side almost does as well. Eovaldi always seems to step up in big games and he will most likely pitch deeper into the game than Cole. With a game that feels like a coin flip between two teams that know each other extremely well, how can you not be tempted to grab a +145 / +150 price on the Red Sox?

Caesars Sports Book Logo

Interested in placing a bet on Friday’s Yankees vs Red Sox Opening Day clash? Caesars Sports is offering up to a $1,500 match bet for first-time deposits in New Jersey, West Virginia, Colorado, Indiana, Iowa, Michigan, Virginia, Tennessee, Arizona, New York and Louisiana.

2022 MLB Division Previews

Sportsmemo’s content team has the 2022 MLB season covered from every angle. Before this afternoon’s first pitch, check out the division previews from JM Sports, which highlight the incoming and outgoing players from each team. Content Manager Kyle Kargel, breaks down the DraftKings prop markets for most home runs, strikeouts and stolen bases. Check ’em out!

AL East
AL Central
AL West
NL East
NL Central
NL West

First Pitch | MLB Opening Day Predictions for April 8

Join Drew Martin and a rotating panel of guests for First Pitch as we break down the daily baseball slate from a betting perspective. The Blue Jays have drawn a lot of attention in the AL East. Can Toronto kick off the season on the right foot with a home win over the Rangers? Join WagerTalk’s team of MLB betting experts every weekday at 1:45pm ET / 10:45am PT for First Pitch as we discuss the baseball betting slate.

MLB Opening Weekend Picks and Predictions |  First Pitch Daily Baseball Betting Preview | April 8

WagerTalk Live Odds Screen

WagerTalkโ€™s live odds screen features up-to-the-minute lines from a variety of offshore and domestic sports books. Track the MLB moneylines, run lines and betting percentages for all of Friday’s Opening Day games, including this Yankees vs Red Sox showdown, from your desktop or phone.

WagerTalk Live Odds Screen

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Meet the Author

Andy Lang has lived in Indianapolis his whole life, and like most people from the Hoosier State, he became fascinated with motor sports. That interest in motor sports turned into a desire to make money off the sport through fantasy contests and sports betting. Like most, he took his lumps when he first got started, but now he is one of the most respected NASCAR bettors in the industry. Andy has expanded that sports betting experience to become profitable in a number of other sports, transforming this interest from a side hobby to a major source of income.

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