UFC Fight Night: Edwards vs Brady Predictions, Picks and Betting Odds March 22

UFC Fight Night Betting Preview

UFC WagerTalk handicapper Andy Lang gives his UFC Fight Night picks and predictions for March 22 with the main event headlined by Leon Edwards vs Sean Brady in a welterweight fight. The main card starts up at 4:00pm ET from O2 Arena in London, England.

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Leon Edwards vs Sean Brady: UFC Fight Night Main Event

Saturday, March 22	UFC Fight Night Betting Notes (Courtesy of Caesars)
Moneyline:	Leon Edwards +140 vs Sean Brady -170
Rounds:	4.5 (Over -215 / Under +165)
Fight Time:	Main Card Starts at 4:00pm ET / 1:00pm PT
Arena:	O2 Arena in London, England
TV:	ESPN+

UFC Fight Night Predictions

Guram Kutateladze -425 vs Kaue Fernandes +330 

I thought Guram would be fighting for a UFC title at this point after making  his debut against Gamrot, and getting the decision win in an amazing fight, but he dropped his next 2 fights to Brener and Ismagulov, and it just doesn’t seem like he’s that interested in being a contender.

He’s had 3 fights since that 2020 fight against Gamrot, and his only win is against a guy making his UFC debut, but I expect him to win this one everywhere this fight takes place.

Don’t pay much attention to Fernandes’s last fight as he  beat Yahya, who’s one of the worst fighters on the UFC roster, instead go look at the Diakiese fight.

He lost a split, but he didn’t do much on offense, and Diakiese was able to take him down and neutralize him, and in round 3 Fernandes didn’t have much gas left in the tank.

Guram has good  movement, and good enough striking to keep Fernandes on the back foot, and even though I’ve watched Guram get tired late, Fernandes isn’t the guy to expose that weakness. If Guram is focused, this should be a schooling in the striking and wrestling. Guram is the pick.

Nathan Fletcher -148 vs Caolan Loughran +124 

This is a striker vs grappler type of matchup as Loughran will want this to  stay on the feet and Fletcher will try to get it to the ground. Honestly, I don’t really care who wins this fight, I’m just taking this fight over 2.5 or to go the distance.

All 3 of Loughran’s UFC fights have gone the distance as  he’s a decent striker, but in the UFC it’s point fighting as opposed to big knockouts.

Loughran has a huge head with a granite chin so he’s not getting knocked out by Fletcher, and he’s a strong stocky guy who is going to be tough to takedown and next to impossible to submit as his only 2  losses are by decision.

Fletcher is 9-1 as a pro, but not against great  competition, he’s not exactly a killer so I just don’t see a finish in this one. Take the overs, I don’t care who wins.

Shauna Bannon -175 vs Puja Tomar +145 

Again, I don’t care who wins, I’ll be taking this fight to go the distance. Tomar is valuable to UFC as she has a huge social media following in India, and that’s a valuable audience to UFC, and I didn’t expect much from  her in her debut, but give her credit.

She was aggressive, threw solid volume, and got the win against dos Santos who laid an egg. Bannon is  kind of similar in that she isn’t polished, but she’ll give you 3 good rounds, she’ll throw volume, and land some shots, but she’s not challenging for a title.

Neither of these women hit hard enough to get the KO, and they don’t  know how to submit so I see almost no paths for a finish here. This fight to  go the distance is probably my favorite parlay piece on the card.

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Christian Leroy Duncan -550 vs Andrew Pulyaev +410 

Pulyaev showed good cardio, good durability, solid body kicks, and good takedown defense on Contender Series, but his opponent underperformed, and I think Duncan has the tools to cruise through this fight.

Duncan is coming off a loss to Gregory Rodrigues, but he had gotten 2 finishes before  that, and Rodrigues was able to have success with takedowns and top control, but I haven’t seen Pulyaev implement that game plan.

Duncan’s  striking is going to be better than anything Pulyaev has faced, and I see Duncan doing some solid damage to Pulyaev.

Pulyaev is tough, and he  could make round 3 tough for Duncan, but I think CLD will win too many  exchanges on the feet. Duncan by decision.

Marcin Tybura -130 vs Mick Parkin +110 

Parkin is undefeated, but that’s been a bad thing in the UFC in 2025 as lots  of guys have been handed their first loss.

Parkin has good striking on the feet, and he’s gotten better every fight as he trains with some top fighters, but this fight is all about if Tybura gets it to the ground.

If Parkin keeps it on the feet, he’ll have the volume to point his way to a decision win, but if  Tybura gets on top, Parkin is big trouble.

Tybura’s only recent losses are to Volkov and Aspinall (top ranked fighters), and a random arm bar loss to Spivac when Tybura was on top.

Tybura’s top game is devastating, and I  don’t think Parkin can get up too many times if he gets taken down. This is  big step up for Parkin as he’s fought Usman, Brzesi, Machado, and Pogues in the UFC, I just think Tybura only needs to get this down once before a finish is possible. I’ll take Tybura.

Loneer Kavanaugh -410 vs Felipe Dos Santos +320 

Kavanaugh looks to be the real deal coming off of Contender Series, and he gets a step up in competition in Dos Santos here who has lost 2 out of  3, but to Kape and Lima, no shame in those losses. It’s just that I don’t see greatness with Dos Santos.

Sure, he went the distance with Kape and  Lima, but was he ever a threat to win? Not really. He was outstruck, and controlled on the ground, and his win was a split against Altamirano.

I like Kavanaugh’s striking is more powerful, and damaging, and since he got his  first UFC jitters out of the way, I like him to be even more confident than in the first fight.

I like Dos Santos, I think he’s good, but just not good enough  to scare Kavanaugh on the feet, and his ground game isn’t good so there’s no worry for Kavanaugh there. Kavanaugh by decision here.

Jai Herbert -130 vs Chris Padilla +110 

I like Herbert in this fight. In Herbert’s last fight, he fought another younger  fighter and was the quicker fighter who did more damage on the fight and in  the clinch, and I think he could do the same to Padilla.

Padilla has been  better in the UFC than I thought he would be, as he got the wins against Llontop and Rongzhu, but I though Rongzhu was fighting him well and winning some of the striking exchanges until Padilla landed a great elbow that caused a doctors stoppage, and the sub against Llontop was mostly  due to Llontop fighting like a moron and trying the same move three times until Padilla timed it right and got the submission.

Herbert is a veteran that  doesn’t make those mistakes, and I wouldn’t be surprised if Herbert uses  his reach and speed to frustrate Padilla for 3 rounds.

I love this fight to go the distance as both guys are durable and tough to hit, but Herbert is the ML pick.

Morgan Charriere -166 vs Nathaniel Wood +140 

I’m a big Charriere fan, and I thought he got robbed against Mariscal 2  fights ago, but he got the KO win against Miranda in his last fight.

The worry with him coming into the UFC was his lack of volume and aggression, but he’s proved that to not be an issue. His striking is solid on  the feet, and he’s very strong in the clinch, tough to take down, and tough to hit.

Wood is going to try and get the leg kicks going, but outside of that I  think Charriere has the advantage everywhere else. Wood is durable, so is  Charriere, so I like this to go the distance. Charriere by Decision is the play.

Jordan Vucenic -345 vs Chris Duncan +275 

Vucenic all day in this one. I’ve never been impressed with Duncan as he  has a win on CS where he was getting beat up, and he landed a hail mary  shot to get the win.

Then he barely won a split over Omar Morales who got  cut from UFC, and in his last fight he was losing until Oki put his neck in a  guillotine to give Duncan another improbable win.

Credit Duncan with  getting those wins, but toughness, durability, and winning fights you were  losing will eventually run out, and I think it runs out here.

Vucenic is a  submission specialist who had to fight Kutateladze in his UFC debut, and  even though he lost, he took it to decision, and held his own.

I think Vucenic is going to be more technical with the body control, and takedowns  and I wouldn’t be surprised if he gets the submission win. Duncan is a fade as he steps up in competition, I’ll take Vucenic in this one.

Molly McCann -300 vs Alexia Thainara +240 

I just have no idea what we’re going to get from Molly McCann at this point.  It’s a London event so of course she’s fighting, but she’s 1-3 in her last 4, and just lost pretty bad to Bruna Brasil.

If McCann is on her A game, she  should be more polished and powerful, but Thainara is a dog. She comes  forward, she can get takedowns, and we saw great kicks from her on Contender Series.

She leaves herself open to get hit so Molly will have plenty of chances to hit her clean, it’s just if Molly is dialed in.

I could see this going the distance, I could see an early finish, I truly don’t know what  we’re getting in this fight.

I won’t bet on it, but this fight could be one of the  best fights of the night based on how aggressive both fighters can be. I’ll lean to McCann to win, but certainly not at -300.

Gunnar Nelson -135 vs Kevin Holland +114 

I’m all aboard the fade Kevin Holland train. He has 1 win in his last 5 fights, and he seems more motivated by being funny, and getting fight paychecks rather than improving and looking for wins.

His performance in January  was embarrassing as he was quickly submitted by de Ridder, and now he’s  fighting 7 weeks later?

I just can’t take him serious, which is too bad  because he can be a good striker, and a solid submission specialist on the ground, but we just haven’t seen much of it.

Nelson is a grappler who had  to take time off after losing to Gilbert Burns, but he’s returned and won both  of his fights, I just wish he would fight more often as this is a 2 year break for him.

I think Nelson gets this to the ground, and it’s only a matter of time  before he gets a submission against Holland as de Ridder made it look easy against Holland, and Nelson is as talented as de Ridder. Nelson is the pick, sprinkle on the submission prop.

Carlos Ulberg -225 vs Jan Blackowicz +185 

If Jan can’t get this fight to the ground, I think he’s in trouble. Ulberg’s  striking is some of the scariest in the UFC as it’s powerful, and accurate,  but he showed he can go the distance and win like he did against Oezdemir.

We haven’t seen Jan in almost 2 years, and he’s in his late 30s, and in his last fight that he lost in a split decision against Pereira, he had a  great first round, and he just faded the longer the fight went. He ate a  bunch of leg kicks, his nose was busted up, and Pereira didn’t even look  that good in that fight.

Jan was really low volume, and had no finishing  ability after the first round. I think Jan will look decent in the first, but unless he gets the finish, I think the younger, more athletic fighter in Ulberg will start landing strikes eventually getting the win over a tired Jan. Ulberg is the play.

UFC Fight Night Main Event: Leon Edwards vs Sean Brady

You can poke serious holes in Leon Edward’s results. He beats Nate Diaz  who only fought once more in the UFC, he was losing handily to Usman  before landing the big head kick, he beat Usman in the rematch when  Usman looked washed, then he beat a washed Colby Covington, and then  got dogwalked by Belal Muhammad. So what’s his big, impressive win? 

Brady has won 2 straight over Gastelum and Burns, and those were at least convincing wins. Brady is going to try and get Edwards on the  ground, and he’ll have some success as his takedowns and wrestling are elite. Can he get the finish and/or do it for 5 rounds is the question.

Leon Edwards can be taken down, there’s no question as Belal took him down 9  times, and Usman took him down 9 times in their 2 fights, and even Covington got 2 takedowns, but he can get back up and I wonder if that’s  going to zap the energy of Brady leading this to be a fight that’s on the feet in the later rounds, which is a big advantage for Edwards.

I think this fight goes the distance, and Edwards squeaks out a close win, but I certainly  wouldn’t be surprised to see Brady do enough to win so I won’t bet on a  side, I’ll just take the overs in this fight.

The only 2 fights that have ended by finish for Edwards recently have been the crazy head kick, and an eye poke in the Belal fight.

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