Premier League Odds, Schedule and Predictions for February 21-23

Get English Premier League Odds for February 21-23

WagerTalk Premier League handicapper Kevin Dolan presents his Premier League predictions heading into February 21-23 scheduled matches. He gives betting previews for key matches including Leicester vs Brentford, Manchester City vs Liverpool and more.

Which Premier League teams is he looking to pick up points and which will have goals being scored? Read his betting preview now!

Leicester vs Brentford | February 21 | 3:00PM ET

Leicester +250 | Brentford +105 | Draw +275

Leicester City continued their downward spiral in the Premier League with yet another loss against Arsenal last weekend, their ninth defeat across their last ten league games in all.

Thankfully for the Foxes however, the teams around them have failed to take much advantage, with Leicester still only two points adrift from safety currently as they desperately look to stay afloat in the Premier League for another season.

Standing in their way on Friday night is a Brentford team that has been the epitome of consistency across recent seasons, with an average placement of 12.6 over the last three years, and currently sit in 11th spot this season also.

The Bees came off an impressive win over West Ham last weekend, and have won each of their last three games on the road as well, including a 5-0 blowout against Leicester’s relegation neighbors Southampton last month.

However, despite blowing out Leicester also 4-1 in their previous meeting back in December, Brentford haven’t beaten Leicester across either of their two prior meetings in the East Midlands, so it’s possible the Foxes can rely on some fervent home support to get them over the line once again.

The one thing that has remained consistent in this fixture however is goals, with both teams finding the back of the net in each of their last six meetings.

The combination bet of Both Teams to Score & Over 2.5 goals is going off at -120 right now and that’s the way we’d look to play this one on Friday.

Premier League Prediction: Both Teams to Score & Over 2.5 (-120)

Southampton vs Brighton | February 22 | 10:00AM ET

Southampton +425 | Brighton -170 | Draw +335

A bit of a south coast derby here on Saturday as surging Brighton, who have won three of their last four games on the road, head due west looking to close that gap on the European spots above them by taking on Southampton this weekend.

However, despite Brighton’s solid recent run away from home, they did suffer a massive 7-0 humiliation against Nottingham Forest in their last road trip, so they can’t be overly complacent ahead of this one, even taking on the Premier League’s worst team.

For Southampton, it’s been an admittedly miserable season for them overall, still yet to break Derby’s points total as the worst Premier League team in history, and with just one win in the league since early-November, even overcoming that low benchmark may be seen as a success for them.

Saints have however been fairly competitive against Brighton at home in this fixture, losing just two of their last six meetings at St. Mary’s, and with Southampton conceding 58% of all of their goals on the road this season, they’ll hope they have enough to keep this one tight on Saturday.

Recent results at home however would suggest otherwise, with Saints conceding 3+ goals in six of their last seven Premier League appearances at this venue.

No team has been losing more at HT this season than Southampton have, owning a poor 3-8-14 record overall, and that could well be the angle in here on Saturday by taking Brighton to win HT/FT at a nice plus money price this weekend.

Premier League Prediction: Brighton Halftime / Full Time (+155)

Manchester City vs Liverpool | February 23 | 11:30AM ET

Manchester City +185 | Liverpool +130 | Draw +285

In what should arguably be a much bigger game here on Sunday, Liverpool travel over to Manchester City this weekend holding a huge advantage in the table over the current Premier League champions, so much so that even a win for Manchester City in this one would likely do little in helping them to reclaim their crown.

That said however, City can nonetheless put a serious dent in Liverpool’s own title ambitions, with Arsenal potentially only five points back from the Reds providing they can win their game in hand, and with Liverpool not in the best of form currently, winning just one of their last three Premier League games overall, we could be in for some late drama to close out the season.

Despite the separation in the table between these two teams currently, Manchester City have actually been in the slightly better form of the two based on recent home/away splits, with City registering 2.17 PPG across their last six home starts, while Liverpool have registered a slightly lower 2.00 PPG across their last six road starts.

Those recent home starts for Manchester City have included solid teams such as Chelsea and Newcastle also, while Liverpool’s only wins on the road across 2025 so far have come against Bournemouth and Brentford.

With both teams in some inconsistent domestic form overall, plus their European form, with City looking to dust themselves off from a midweek Champions League exit by Real Madrid, while Liverpool only have a two week turnaround to the Round of 16 matchups, we’re expecting an extremely competitive encounter here on Sunday between these two heavyweights, and one that could well end in a stalemate as a result.

Premier League Prediction: Draw (+285)

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